Testing The Anti-Aging Effects Of Various Plant Extracts In Vivo And In Vitro

Authors

  • Triana Febriyanti Universitas Lampung
  • Asep Sukohar Universitas Lampung
  • Citra Yuliyanda Pardilawati Universitas Lampung
  • Andi Nafisah Tendri Adjeng Universitas Lampung

DOI:

https://doi.org/10.53089/medula.v14i3.1041

Keywords:

Anti Aging, Ekstrak, In Vivo, In Vitro

Abstract

The outermost and largest organ in our body is the skin. Skin can experience aging when exposed to sunlight. Sunlight contains ultraviolet. Exposure to ultraviolet (UV) radiation causes damage to the skin and can lead to photoaging. Photoaging can be prevented with antioxidant compounds. Many plant extracts or synthetic compounds act as anti-aging agents. These plant extracts become active ingredients that can be formulated into pharmaceutical preparations. Plant extracts that have anti-aging potential include red cabbage, kepok banana peel, red pomegranate, moringa leaves, butterfly pea flower, black cumin seeds and libo fruit. To prove this, a test was carried out. The testing carried out can be in the form of in vivo and in vitro testing methods. This research was carried out using the article review method and obtained several journals from online literature, local journals and international journals, namely electronic searches with the keywords anti-aging, in vitro, in vivo on the website, namely Google Scholar. The number of journals used in this review was 11 journals spanning the last eight years. The results of the article review study showed that several methods used were UV-VIS spectrophotometer, DPPH method, anti-elastase, as well as tests on rats, mice and guinea pigs. From the results of the review of articles on plant extracts, most of them use in vivo tests on experimental animals.

References

Sugihartini N, Nuryanti E. Formulasi Krim Ekstrak Daun Kelor (Moringa oleifera) sebagai Sediaan Antiaging. Berkala Ilmu Kesehatan Kulit dan Kelamin. 2017; 29(1): 1-7.

Lee LY, Liu SX. Pathogenesis of Photoaging in Human Dermal Fibroblast. Int J Dermatology Venereol. 2021; 3(1): 37-42.

Iskandar B, Tartilla R, Lukman A, Leny, & Surboyo MDC. Uji Aktivitas Anti-aging Mikroemulsi Minyak Nilam (Pogostemon cablin Benth.). Majalah Farmasetika. 2022; 7(1): 52–64.

Putri AR, Suhartinah, Untari MK. Uji Aktivitas Krim Anti-Aging Ekstrak Etanol Daun Bayam Merah (Amaranthus tricolor L.) pada Kulit Punggung Kelinci New Zealand yang dipapar Sinar UV-A. Indonesian Journal of Pharmaceutical. 2023; 3(1): 1-15.

Nurrahmah AR, Harjono, Wijayanti N, Priatmoko S. Optimasi Ekstraksi Dan Uji Aktivitas Antioksidan Bunga Tulip Afrika (Spathodea Campanulata P) Dengan Metode Ultrasound Assisted Extraction. Indonesian Journal of Chemical Science. 2023; 12(1): 94-102.

Maretta G, Fitriya I, Putra RE, Ramadhani UKS. Efek Pemberian Ekstrak Kulit Pisang Kepok (Musa acuminate x balbisiana) Terhadap Kulit Mencit (Mus musculus) Yang Terpapar Sinar Ultraviolet. Jurnal Biologi. 2023; 16(2): 301-308.

Riliani M, Pangkahila W, Wiraguna. Pemberian Krim Ekstrak Daun Sukun (Artocarpus altilis) Mencegah Peningkatan Jumlah Melanin Kulit Marmut (Cavia porcellus) Yang Dipapar Sinar Ultraviolet B. Majalah Kesehatan PharmaMedika. 2017; 9(2): 69-78.

Purnamasari R dan Widiyanto B. Pengaruh Krim Ekstrak Clitoria Ternatea Terhadap Jumlah Neutrofil Kulit Yang Dipapar Sinar Ultraviolet B. Malahayati Health Student Journal. 2023; 3(10): 3264-3272.

Sari W, Chiuman L, Ginting SF, Ginting CN. Pengaruh Krim Ekstrak Jintan Hitam (Nigella sativa) Terhadap Kadar Kolagen dan Hidrasi Kulit Tikus (Rattus norvegicus) Galur Wistar Jantan Yang Dipapar Sinar Ultraviolet-B. Jurnal Ilmu-ilmu Hayati. 2020: 19(3A); 321-325.

Riliani M, Pangkahila W, Wiraguna. Pemberian Krim Ekstrak Daun Sukun (Artocarpus altilis) Mencegah Peningkatan Jumlah Melanin Kulit Marmut (Cavia porcellus) yang Dipapar Sinar Ultraviolet B (UVB). Majalah Kesehatan PharmaMedika. 2017: 9(2); 69-78.

Subchan P, Putri RS, Muna NI, Hutapea CM, Cahyani E, Hidayah N. Ekstrak Bunga Telang (Clitoria ternatea L.) Menghambat Peningkatan Ekspresi Gen MMP-1 pada Kulit Tikus Wistar yang Terpapar Sinar Ultraviolet-B. Journal of Midwifery and Health Science of Sultan Agung.2022; 1(2): 13-21.

Widiyanto B, Yuniarifa C, Purnamasari R. Efek Perlindungan Ekstrak Bunga Telang (Clitoria ternatea L.) Terhadap Densitas Kolagen Dari Paparan Sinar UVB. Jurnal Sehat Indonesia. 2024; 6(1): 175-182.

Rauap ISBtA, Sugiritama IW, Linawati NM, Arijana IGKN. The effect of red-cabbage (Brasscia oleracea L. var capitata f.rubra) ethanolic extract in cream preparation on dermis-elastic fibra thickness in male Wistar after ultraviolet-B rays exposure. Intisari Sains Medis.2018; 9(3): 127-130.

Soejanto AS. Pemberian Kriam Ekstrak Metanolik Buah Delima (Punica granatum) Menghambat Penurunan Jumlah Kolagen Dermis Kulit Mencit (Mus gusculus) Yang Dipapar Sinar Ultraviolet-B. Indonesian Journal of Anti Aging Medicine. 2017; 1(1): 1-9.

Natanael GI, Simorangkir GF, Purba NP, Tambunan MPBr, Amansyah A, Nasution AN. Potensi Antioksidan Dan Anti-Elastase Ekstrak Daun Kelor (Moringa Oleifera). Jurnal Keperawatan. 2021; 4(1): 69-76.

Amin NYA, Naspiah N, Rusli R. Formulasi Sediaan Krim Anti-Aging Berbahan Aktif Ekstrak Buah Libo (Ficus variegate,Blume). Proceeding of the 8th Mulawarman Pharmaceuticals Conferences; 20-21 November 2018; Samarinda; 2018

Published

2024-04-18

How to Cite

Febriyanti, T., Sukohar, A., Pardilawati, C. Y. ., & Adjeng, A. N. T. . (2024). Testing The Anti-Aging Effects Of Various Plant Extracts In Vivo And In Vitro. Medical Profession Journal of Lampung, 14(3), 593-601. https://doi.org/10.53089/medula.v14i3.1041

Issue

Section

Artikel

Most read articles by the same author(s)

1 2 > >>