Antibacterial Activity of Mauli Banana (Musa acuminata) Peel Extract Against Methicillin Resistant Staphylococcus aureus
DOI:
https://doi.org/10.53089/medula.v9i4.229Keywords:
antibacterial activity, mauli banana peel, methicillin resistant Staphylococcus aureusAbstract
MRSA infection is an urgent global health problem. Synthetic or natural antibacterials should be developed as an effort to overcome the problem. The mauli banana peel contains potential antibacterial compounds such as flavonoids, tannins, saponins, alkaloids, and terpenoids. The purpose of this study is to determine the antibacterial activity of mauli banana peel extract (Musa acuminata) against methicillin resistant Staphylococcus aureus (MRSA). The design of this study was true experimental descriptive, with a post-test control group design. This study examined the antibacterial activity of mauli banana peel extract at concentrations of 100%, 50%, 25%, 12.5%, and 6.25% against MRSA bacteria by measuring inhibitory zone, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC). The results of this study showed that mauli banana extract has antibacterial activity against MRSA with the average diameter of inhibition zone ranging from 23,963 mm to 11,075 mm. The MIC obtained at concentrations of 6.25% and MBC at extract with concentration 50%. One-Way Anova test obtained p value = 0,000 (p <0.05) which means there is a significant difference. Based on the experiment, we can conclude that there is antibacterial activity of mauli banana peel extract (Musa acuminata) against methicillin resistant Staphylococcus aureus (MRSA).
References
WHO. Antimicrobial resistance: global report on surveillance [Internet]. Geneva; 2014. Tersedia dari: www.who.int
Chen C, Huang YC. New epidemiology of Staphylococcus aureus infection in Asia. Clin Microbiol Infect. 2014; 20(7):605–23.
Mendes RE, Mendoza M, Banga Singh KK, Castanheira M, Bell JM, Turnidge JD, et al. Regional resistance surveillance program results for 12 Asia-Pacific nations (2011). Antimicrob Agents Chemother. 2013; 57(11):5721–6.
Mahmudah R, Soleha TU, Ekowati C. Identifikasi Methicillin-Resistant Staphylococcus aureus (MRSA) pada tenaga medis dan paramedis di ruang Intensive Care Unit (ICU) dan ruang perawatan bedah Rumah Sakit Umum Daerah Abdul Moeloek. 2013; 2(4):70–8.
Karchmer AW, Bayer AS. Methicillin-Resistant Staphylococcus aureus : an evolving clinical challenge. Clin Infect Dis. 2008; 46(Suppl 5):342–3.
Normayunita S, Anam S, Khumaidi A. Aktivitas antibakteri fraksi ekstrak kulit buah mentah pisang ambon (Musa paradisiaca var . sapientum) terhadap Staphylococcus aureus. Online J Nat Sci. 2015; 4(3):300–9.
Balouiri M, Sadiki M, Ibnsouda SK. Methods for in vitro evaluating antimicrobial activity : a review. J Pharm Anal. 2016; 6(2):71–9.
Madan J, Singh R. Formulation and evaluation of aloe vera topical gels. Int J Pharm Sci. 2010; 2(2):515–51.
Soleha TU. Uji Kepekaan terhadap Antibiotik. Juke Unila. 2015; 5(9):3–7.
Ngajow M, Abidjulu J, Kamu VS. Pengaruh antibakteri ekstrak kulit batang matoa (Pometia pinnata) terhadap bakteri Staphylococcus aureus secara in vitro. J MIPA UNSRAT. 2013; 2(11):128–32.
Zahro L, Agustini R. Uji efektivitas antibakteri ekstrak saponin jamur tiram putih terhadap Staphylococcus aureus dan Eschercia coli. UNESA J Chem. 2013; 2(3):2–7.
Cushnie TPT, Lamb AJ. Antimicrobial activity of flavonoids. Int J Antimicrob Agents. 2005; 26:343–56.
Wiley J, Chao S, Young G, Oberg C, Nakaoka K. Inhibition of methicillin-resistant Staphylococcus aureus ( MRSA ) by essential oils. Flavour Fragr J. 2008; 23:444–9.
Karuppiah P, Mustaffa M. Antibacterial and antioxidant activities of Musa sp . leaf extracts against multidrug resistant clinical pathogens causing nosocomial infection. Asian Pac J Trop Biomed. Asian Pacific Tropical Biomedical Magazine. 2013; 3(9):737–42.
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