Management Neurogenic Pulmonary Edema in Male 60 Years Old with Massive Ischemic Stroke in RSUD Jendral A. Yani Kota Metro


  • M. Panji Bintang Gumantara Medical Faculty Lampung University
  • Halomoan Simon Tambunan Medical Faculty Lampung University


ARDS, Neurogenic Pulmonary Edema, Stroke Infarct


Neurogenic Pulmonary Edema (NPE) is a pulmonary compromise condition due to severe damage of the central nervous system that causes symptoms similar to ARDS accompanied by pulmonary edema. NPE often occurs in traumatic brain injury (TBI), hemorrhage, recurrent seizures, and epilepsy. Stroke is a focal or general acute neurological deficit condition during more than 24 hours caused by cerebrovascular factors. In patient with extensive stroke infarction of the brain can cause suppression of the respiratory center in the brain so that stroke patients can get complications in the respiratory system that aggravate the patient's condition. This case report described a 60-year-old man with decreased consciousness and weakness of the left limbs since 6 hours before entering hospital with shortness of breath, reddish coughing phlegm, fever, rapid and shallow breathing. Management was given to the patient in pharmacological and non-pharmacological collaborative therapies. Intensive care was planned in the Intensive Care Unit (ICU) formechanical ventilator. The patient's prognosis in this case report wasad malam. The purpose of this case report is to find out the description of clinical problems, identify the risk factors as the cause and provide the best management for patients.


Rianawati SB, Munir B. Buku ajar neurologi.. Malang: Sagung Seto; 2017.hlm.3-27

Mutiasari D. Ischemic stroke: symtomps, risk factors, and prevention. Jurnal Ilmiah Kedokteran 2019. Medika Tadulako. 2019;6(1):1-14.

PERDOSSI.Guideline stroke 2011. Indonesia: Persatuan Dokter Spesialis Saraf Indonesia; 2011.Hlm. 1-131.

Park SM, Kim JM, Youn YC, Kwon OS, Bae J. Neurogenic pulmonary edema following acute cerebral infarction. Jurnal of Neocritical Care. 2016; 9(2):171-3.

Sedy J, Kunes J, Zicha J. Pathogenetic mechanism of neurogenic pulmonary edema. 2015; 1(1):1-45.

Finsterer J. Neurological perspective of neurogenic pulmonary edema. European Neurology. 2019 ; 81:94-101.

Balofsky A, Goerge J, Papadakos P. Handbook of clinical neurology. 3rd series. Wijdicks EFM Kramer AH. USA: Elsevier;2017. hlm. 33-48.

Saracen A, Kotwica Z,Wozniak-kozek A, Kasprzak P. Neurologic pulmonary edema in aneurysmal subarachnoid hemorrhage. Springer International Publishing. 2016; 1(1):1-4.

Hedge A, Prasad GL, Kini P. Neurogenic pulmonary oedema complicating traumatic posterior fossa extradural haematoma: case report and review.Taylor and Francis Group. 2016; 1(1):1-4

Yasui H, Arima H, Hozumi H, Suda T. Neurogenic pulmonary edema without norephinephrine elevation. The Japanese Society of Internal Medicine.2018 28;57:2097-8.

Busl KM, Bleck TP. Neurogenic Pulmonary Edema. Critical Care Medicine. 2015; 43(8):1710-15.

AHA/ASA.2018 Guidelines for the early management of patientswith acute ischemic stroke.USA: American Heart Association/ American Stroke Association; 2018. hlm. 1-54

Zao H, Lin G, Shi M, Gao J, Wang Y, Wang H, dkk. The mechanism of neurogenic pulmonary edema in epilepsy. The Physiological Society of Japan and Springer. 2014; 64:65-72.

Chen W, Huang C, Chen J, Tai HC, Chang S, Wang Y. ECG abnormalities predict neurogenic pulmonary edema in patients with subarachnoid hemorrhage. American Journal of Emergency Medicine. 2015;34(2016):79-82.

Mutoh T, Kazumata K, Ueyama-mutoh T, Taki Y, Ishikawa T. Transpulmonary thermodilution-based management of neurogenic pulmonary edema after subarachnoid hemorrhage. The American Journal of Medical Science. 2015; 350(5):415-9.



How to Cite

M. Panji Bintang Gumantara, & Halomoan Simon Tambunan. (2021). Management Neurogenic Pulmonary Edema in Male 60 Years Old with Massive Ischemic Stroke in RSUD Jendral A. Yani Kota Metro. Medical Profession Journal of Lampung, 9(4), 699-704. Retrieved from