Quercetin On Tea Parasites As A Therapy For Hypertension

Authors

  • Syfa Dinia Putri

DOI:

https://doi.org/10.53089/medula.v10i2.72

Keywords:

Hypertension,quersetin, tea parasite

Abstract

Hypertension is still a big challenge in world. This disease is sometimes not realized by the sufferer. Hypertension is known by increased systolic blood pressure greater than 140 mmHg and / or diastolic greater than 90 mmHg on two measurements with an interval of 5 minutes in a state of resting enough (calm). The management of hypertension can be done by using drugs or by modifying lifestyle. Treatment of hypertension can be done using traditional medicines. Various studies have shown that tea parasites can lower blood pressure because tea parasites contain flavonoids. One of the powerful flavonoids is quercetin. These compounds act as antioxidants by releasing or donating hydrogen ions to peroxy free radicals to make them more stable. This activity blocks the oxidation reaction of bad cholesterol (LDL) which causes blood to thicken, thus preventing the deposition of fat on the walls of blood vessels. Quercetin also has the potential to increasing Nitric Oxide (NO) production in endothelial cells. In this case, the tea parasite containing quercetin is thought to have an effect on lowering blood pressure. So the parasite tea can be used as an antihypertensive.

References

World Health Organization. Clinical guidelines for the management of hypertension. WHO; 2019.

Beevers G, Lip GYH, O’brien E. ABC of hypertension: The pathophysiology of hypertension. BMJ. 2006; 322:912-6.

Tedjasukmana P. Tatalaksana hipertensi. Cermin Dunia Kedokteran. 2012; 39(4):251-255.

Ismarani, Pradono DI, Darusman LK. Mikroenkapsulasi ekstrak formula pegagan kumis kucing sambiloto sebagai inhibitor angiotensin I converting enzyme secara in vitro. Jurnal Agribisnis dan Pengembangan Wilayah. 2011; 3(1):11-24.

Balasuriya BWN, Rupasinghe HPN. Plant flavonoids as angiotensin converting enzyme inhibitors in regulation of hypertension. 2011; 5:172-188.

Simanjuntak PT, Parwasi LE, Lenny S, Tamat, dan Murwani R. Isolasi dan identifikasi senyawa antioksidan dari ekstrak benalu teh scurulla oortiana (korth) danser (loranthaceae). Jurnal Ilmu Kefarmasian Indonesia. 2004; 2(1):6-9.

Capasso R, Aviello G, Romano B, Atorino G, Pagano E, and Borelli F. Inhibitory effect of quercetin on rat trachea contractility in vitro. Journal of Pharmacy and Pharmacology. 2009; 61(1):115-119.

Eno AE, Ibokette UE, Ofem OE, et al. The effects of a nigerian specie of viscum album (mistletoe) leaf extract on the blood pressure of normotensive and doca-induced hypertensive rats. Nigerian Journal of Physiological Sciences. 2004; 19(1-2):33-38.

Athiroh N. Mekanisme kerja benalu teh pada pembuluh darah. Jurnal Kedokteran Brawijaya. 2012; 27(1).

Vanhoutte PM, Shimokawa H, Tang EM, Feletou M. Endothelial dysfuncyion and vascular disease. Acta Phsyologica. 2009; 196:193-222.

Boulanger, CM dan Vanhoutte PM. The endothelium: a pivotal role in health and cardiovascular disease. 1994:9-24.

Athiroh Nour AS. Kontraktilitas pembuluh darah arteri ekor tikus terpisah dengan atau tanpa endotel setelah pemberian ekstrak scurulla oortiana (benalu teh). Jurnal Universitas Islam Malang. 2009; 3(4):31-34.

Published

2020-09-19

How to Cite

Syfa Dinia Putri. (2020). Quercetin On Tea Parasites As A Therapy For Hypertension. Medical Profession Journal of Lampung, 10(2), 307-311. https://doi.org/10.53089/medula.v10i2.72

Issue

Section

Artikel