Tuberculous Meningoencephalitis in a 20-Year-Old Male With Human Immunodeficiency Virus : A Case Report


  • Fitriyani Fitriyani
  • Andriani Dearta Saragih Universitas Lampung



Meningitis, Encephalitis, Meningoencephalitis, meningitis, encephalitis, meningoenchepalitis


Meningoencephalitis is a neurological condition that contains both symptoms of meningitis and encephalitis – inflammation of the meninges (lining of the CNS) and inflammation of the brain tissue itself. Fever, headache, meningismus, changes in mental status, neurological deficits and/or seizures are symptoms of meningoencephalitis. Mycobacterium tuberculosis infection in the central nervous system can cause several diseases, one of which is meningitis. Meningitis is an inflammatory condition of the meninges caused by an infective agent. If this meningeal infection process affects the brain parenchyma, it is called meningoencephalitis. Meningoencephalitis patients who present with decreased consciousness should be considered whether they have tuberculous meningitis (TB), especially if there is a history of pulmonary tuberculosis, alcohol use, Human Immunodeficiency Virus (HIV) infection or other conditions associated with impaired immune response. The diagnosis of TB meningoencephalitis is often delayed due to late presentation of the clinical picture, resulting in high morbidity and mortality rates. TB meningoencephalitis is also associated with a high incidence of sequelae that persist for a long time and tends to have a poor prognosis, so immediate treatment or management is needed for patients. We report the clinical presentation and management of a case of a man with meningoencephalitis and a history of HIV disease. A 20 year old man with the main complaint of loss of consciousness and pain throughout the body. Additional complaints include fever, dizziness, trembling in both hands accompanied by nausea and vomiting since 8 days of SMRS. The patient was then taken to the emergency room at Abdul Moeloek Regional Hospital with complaints of loss of consciousness, body shaking and pain throughout the body. Cough (-), runny nose (-), vomiting (-), diarrhea (-), head trauma (-), coma consciousness. Previously the patient had been diagnosed with HIV. Physical examination showed meningeal stimulation (+), Management of meningoencephalitis using antibiotic therapy. Several neurological disorders can occur in Meningoencephalitis patients.

Author Biography

Fitriyani Fitriyani




Evani S, Junaidi FJ. Laporan Kasus: Penanganan Status Epileptikus Refrakter Pada Anak Dengan Meningoensefalitis Di Rumah Sakit Tipe D. Callosum Neurology. 2019;2(1):1– 7. Https://Doi.Org/10.29342/Cnj.V2i1.4 6.

Slane VH, Unakal CG. Tuberculous Meningitis. StatPearls. 2022.

Riasari. Profil Klinis Pasien Meningoensefalitis. 2021;2(2):44–50.

Ungureanu A, van der Meer J, Bicvic A, Abbuehl L, Chiffi G, Jaques L, Suter-Riniker F, Leib SL, Bassetti CLA, Dietmann A. Meningitis, meningoencephalitis and encephalitis in Bern: an observational study of 258 patients. BMC Neurology, 2021; 21(1).

Hauser SL, Josephson SA. Harrison’s Neurology in Clinical Medicine (4th ed.). Mc Graw Hill Education. 2017.

Kemenkes RI. Profil Kesehatan Indonesia Tahun 2017. Jakarta. 2017.

Yogarajah M. Crash Course Neurology (4th ed.). Elsevier Limited. 2013.

Greenberg D A, Simon R P, Aminoff MJ, Michael J. Clinical neurology (10th ed.). McGraw-Hill Education. 2018.



How to Cite

Fitriyani, F., & Saragih, A. D. (2024). Tuberculous Meningoencephalitis in a 20-Year-Old Male With Human Immunodeficiency Virus : A Case Report. Medical Profession Journal of Lampung, 14(6), 1061-1066.




Most read articles by the same author(s)

1 2 > >>