The Effect of Using Corticosteroid Drugs on the Incidence of Acute Glaucoma

Authors

  • Siti Shafira Elfreda Universitas Lampung
  • Rani Himayani Universitas Lampung
  • Putu Ristyaning Ayu Sangging

DOI:

https://doi.org/10.53089/medula.v13i4.1.731

Keywords:

Acute Glaucoma, Intraokular Pressure, Steroid

Abstract

Based on 2015 data obtained from the Global Burden of Disease Study, around 36 million people in the world or the global population are blind, 12.6 million of them are caused by cataracts, 7.4 million due to refractive disorders, and 2.9 million due to glaucoma. Corticosteroids are an anti-inflammatory class that is usually used in ocular and anterior segment disorders. When taking steroid drugs systemically or using them topically, periocular, or by inhalation, there will usually be an impact in the form of an increase in intraocular pressure which will show the effect within 3-6 weeks after use. This research was conducted as a type of literature review to collect data relevant to the material currently being studied, namely steroid-induced glaucoma. The results of the study showed that Steroid Induced Glaucoma is an eye disorder caused by steroid consumption and are the most common cause of irreversible blindness. This eye disorder is caused by systemic, inhaled, intranasal, or topical steroid induction which can cause an increase in IOP within several months. Treatment that can be recommended for patients to treat this case is with medication in the form of beta-blockers, alpha-2 agonists, and carbonic anhydrase inhibitors. It is also recommended for operative procedures such as lasers, tube shunts and cyclo-destructive procedures.

References

Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014. 121 (11): 2081-90.

Lai, Connie H. Y., Fan, Dorothy, S. P., Chan, dan Jonathan, C. h.. Corticosteroid-induced glaukoma in children. HKJ Ophtamol. 2014. Vol 18 (1).

Gupta S, Shah P, Grewal S. Steroid-induced glaucoma and childhood blindness. Br J Ophthalmol. 2015. 99: 1454-6.

Kiddee W, Trope GE, Sheng L, Beltran-Agullo L, Smith M, Strungaru MH, et al. Intraocular pressure monitoring post intravitreal steroids: a systematic review. Survey of ophthalmology. 2013. 58(4):291-310.

Shan SW, Do CW, Lam TC, et al. New insight of common regulatory pathway in human trabecular meshwork cells in response to dexamethasone and prednisolone using an integrated quantitative proteomics: SWATH and MRM-HR mass spectrometry. J Proteome Res. 2017. 16(10):3753–65.

Ilyas S, Yulianti SR. Ilmu penyakit mata. Jakarta:Badan Penerbit FKUI. 2015. Edisi 5: 1-296.

Phulke S, Kaushik S, Kaur S, Pandav SS. teroid-induced Glaucoma: An Avoidable Irreversible Blindness. J Curr Glaucoma Pract. 2017. 11(2):67-72.

Suharjo SU, Sundari S, Sasongko MB. Kelainan Palpebra, Konjungtiva, Kornea, Sklera dan Sistem Lakrimal. Dalam Suhardjo SU, Hartono. Ilmu Kesehatan Mata. Fakultas Kedokteran Universitas Gadjah Mada. 2012. 111-43.

Ang M, Ti SE, Loh R, Farzavandi S, Zhang R, Tan D, Chan C. Steroid-induced ocular hypertension in Asian children with severe vernal keratoconjunctivitis. Clin Ophthalmol. 2012.6: 1253–8.

Lam CS, Umi Kalthum MN, Norshamsiah MD, Bastion M. Case series of children with steroid-Induced glaucoma. Malays Fam Physician. 2018. 13(3):32-7.

Shroff S, Thomas RK, D'Souza G, Nithyanandan S. The effect of inhaled steroids on the intraocular pressure. Digit J Ophthalmol. 2018. 24(3):6-9.

Csorba A, Soproni A, Maneschg O, Nagy ZZ, Szamosi A. Application of corticosteroid eye drops for allergic eye diseases in children. Orv Hetil. 2019. 160(9):329-37.

Phadatare SP, Momin M, Nighojkar P, Askarkar S, Slingh KK. A comprehensive review on dry eye disease: Diagnosis, medical management, recent developments, and future challenges. Advances in Pharmaceutics. 2014.

Chang CJ, Somohano K, Zemsky C, Uhlemann AC, Liebmann J, Cioffi GA, Al-Aswad LA, Lynch SV, Winn BJ. Topical Glaucoma Therapy Is Associated With Alterations of the Ocular Surface Microbiome. Invest Ophthalmol Vis Sci. 2022. 63 (9): 32.

Andole S, Senthil S. Ocular Surface Disease and Anti-Glaucoma Medications: Various features, Diagnosis, and Management Guidelines. Semin Ophthalmol. 2022. Vol. 1: 1-9.

Published

2023-05-31

How to Cite

Siti Shafira Elfreda, Rani Himayani, & Putu Ristyaning Ayu Sangging. (2023). The Effect of Using Corticosteroid Drugs on the Incidence of Acute Glaucoma. Medical Profession Journal of Lampung, 13(4.1), 144-149. https://doi.org/10.53089/medula.v13i4.1.731