Nasopharyngeal Carcinoma with Multiple Cranial Nerve Palsy in Female Patients 52 Years Old


  • Arilinia Pratiwi Medical Faculty Lampung University
  • Mukhlis Imanto Medical Faculty Lampung University



Case Report, nasopharyngeal carcinoma, multiple cranial nerve palsy


Nasopharyngeal Carcinoma is a malignant disease that appears in the nasopharyngeal area, namely the area above the throat and behind the nose. Nasopharyngeal carcinoma is an example of malignancy in the THT-KL and is the 4th most common malignancy case after breast cancer, cervical cancer, and lung cancer in Indonesia. The etiology of nasopharyngeal carcinoma is multifactorial, namely infection from Epstein Barr virus, genetic, and related to the environment such as consumption of salted fish, smoking habits, food preservatives, mosquito coils, and wood smoke. This case was found in a female patient, 52 years old, who came to Dr. Hospital. H. Abdoel Moeloek with complaints of headache since 2 months ago. Other complaints felt by patients are double vision, ringing in the ears, face feels numb on one side, pelo talk and tongue falling to one side, and nausea and weakness. There was a complaint of a lump appearing on the right neck since 5 months ago before complaints of headache appeared. The results of physical and supporting examinations and biopsy examinations have been carried out and the results obtained refer to the diagnosis of nasopharyngeal carcinoma. Treatment carried out on patients is symptomatic to reduce symptoms and is referred to a higher hospital for further treatment.


World Health Organization. 10 facts about cancer [internet]; 2017 [diakses pada tanggal 29 Oktober 2019 pukul 21.05 WIB] Tersedia dari:

Kementrian Kesehatan RI. Panduan penatalaksanaan kanker nasofaring. Jakarta: Kemenkes RI; 2017.

Ferlay J, Soerjomataram I, Dikshit R, Esher S, Mather C, Forman D, Dkk. Cancer insidence and mortality worldwide: sources, methods, and major patterns in globocan [internet]. United Kingdom: Felay J and associated; 2012 [diakses pada tanggal 27 oktober 2019 pukul 13.00]. Tersedia dari:

Kementrian Kesehatan RI. Situasi penyakit kanker. Jakarta: Kemenkes RI; 2015.

Putri EB. Karakteristik penderita Karsinoma Nasofaring di departemen ilmu kesehatan THT-KL RSUP dr. Hasan Sadikin Bandung periode tahun 2006-2010 [skripsi]. Bandung: Universitas Padjajaran; 2015.

Yenita AA. Penelitian Korelasi antara Latent Membrane Protein-1 Virus Epstein-Barr dengan P53 pada Karsinoma Nasofaring (Penelitian Lanjutan). Jurnal Kesehatan Andalas. 2012. 1(1): 4–6.

Rahman S, Budiman BJ, Subroto H. Faktor Risiko Non Viral Pada Karsinoma Nasofaring. Jurnal Kesehatan Andalas. 2015; 4(3): 988-995.

Zheng, at all. Nasopharingeal carcinoma incidence and mortality in china. Chin J Cancer. 2017. 1(1): 1-8.

Soepardi EA, Iskandar N, Bashiruddin J, Rastuti RD. Buku ajar ilmu kesehatan telinga hidung tenggorok kepala leher. Jakarta: fakultas kedokteran universitas Indonesia. 2008.

Thapa, Narmaya. Diagnosis and Treatment of Sinonasal Inverted Papilloma. Nepalese Journal of ENT Head and Neck Surgery. 2015;1(1).

Kadhoka ZT. Nasopharyngeal carcinoma: past, present, and future directions. Sweden: Departement of oncology institute of clinical science. 2010.

Guo X, Jhonson RC, Deng H, Liao J, Guan L, Nelson GW, dkk. Evaluation of nonviral risk factor for nasopharyngeal carcinoma in a high risk population of Shoutern China. Int J Cancer. 2009; 124: 2942-7.

Kentjono WA. Perkembangan terkini penatalaksanaan karsinoma nasofaring. Jurnal kedokteran tropis Indonesia. 2006. 14(2): 1-39.

Adham M, Kurniawan AN, Muhtadi A, Roezin A, Hermani B, Gondhowiardjo S, Dkk. Nasopharingeal carcinoma in Indonesia: epidemiology, incidence, signs, and symptoms at presentation. Chin J Cancer. 2012. 31(4): 186-196.

Amstrong R, Imrey P, Sann M, Amstrong J, Yu M, Sani S. Nashopharingeal carcinoma in Malaysian chinese: salted fish and other dietary exposures. Int J Cancer. 1998. 77 (1): 228-235.

Widiono K, Yusmawan W, Naftali Z. Perbandingan five year survival rate penderita karsinoma nasofaring pada modalitas kemoterapi dan kemoradiasi. Jurnal Kedokteran Diponegoro. 2017. 2(9): 705-715.



How to Cite

Arilinia Pratiwi, & Mukhlis Imanto. (2021). Nasopharyngeal Carcinoma with Multiple Cranial Nerve Palsy in Female Patients 52 Years Old . Medical Profession Journal of Lampung, 9(4), 609-615.




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