The Effect of Apple (Malus sylvestris mill) as a Natural Ingredient to Prevent Hair Loss


  • Chintya Redina Habsari
  • Merry Indah Sari
  • Yulisna



apple, hair loss hair growth, hair growth


Hair serves to protect the skin from bad influences, such as eyebrows that protect and prevent sweat that will flow to the eyes. While the nose hair functions as filtering the dust on the nose. Hair also has a role in protection against; adverse environment, including cold or hot temperatures, and ultraviolet light. Hair is not uncommon as confidence. Hair loss to cause baldness is a problem that is enough to worry about high self when they interact. Hair loss can be caused by many factors that are organized into endogenous: due to systemic disease, hormonal, nutritional status, intoxication, or a genetic disorder and exogenous factor in the form of stimulus from the environment and hair cosmetics. Today there are many studies of natural plants or herbal ingredients that can be used to treat hair loss. One of the plants that can grow hair is apple. Apples contain procyanin B-2 naturally found in apples. Apple extract is then made for hair tonic or cream proven to accelerate hair growth.


Lin R, Garibyan L, Kimball A, Drake L. Systemic causes of hair loss. Ann Med. 2016;48(6):393–402.

Gonul M, Cemil BC, Ayvaz HH, Cankurtaran E, Ergin C, Gurel MS. Comparison of quality of life in patients with androgenetic alopecia and alopecia areata. An Bras Dermatol. 2018;93(5):651–8.

Paramita K, Listiawan MY, Lrahmadewi Y. Gambaran Dermoskopik Pasien Alopesia (Dermoscopic Features of Alopecia Patient). Period Dermatology Venereol. 2015;27:163–9.

Stephani Y, Putri EA, Irsan A. Tingkat Pengetahuan, sikap dan Perilaku terhadap Kerontokan Rambut dengan Pemakaian Jilbab pada Mahasiswi FK UNTAN. J Cerebellum. 2018;4(2):1067–78.

Ramos PM, Miot HA. Female pattern hair loss: A clinical and pathophysiological review. An Bras Dermatol. 2015;90(4):529–43.

Guo EL, Katta R. Diet and hair loss: effects of nutrient deficiency and supplement use. Dermatol Pract Concept. 2017 Jan 31;7(1):1–10.

Faghihi G, Mozafarpoor S, Asilian A, Mokhtari F, Esfahani AA, Bafandeh B, et al. The effectiveness of adding low-level light therapy to minoxidil 5% solution in the treatment of patients with androgenetic alopecia. Indian J Dermatology, Venerol Leptorology. 2018;84(5):547–53.

Gowda D, Premalatha V, Imtiyaz DB. Prevalence of Nutritional Deficiencies in Hair Loss among Indian Participants: Results of a Cross-sectional Study. Int J Trichology. 2017;9(3):101–4.

Thompson JM, Mirza MA, Park MK, Qureshi AA, Cho E. The Role of Micronutrients in Alopecia Areata: A Review. Am J Clin Dermatol. 2017 Oct;18(5):663–79.

Gur J, Mawuntu M, Martirosyan D. FFC’s Advancement of Functional Food Definition. Funct Foods Heal Dis. 2018;8(7):385–97.

Rohman Y, Putri DRRE, Ardhila NF, Fathimah. Daya Hambat Terendah Ekstrak Kulit Apel Manalagi ( Malus Sylvestris Mill .) Terhadap Bakteri Eschericia Coli. J Islam Nutr. 2018;1(1):26–32.

Almeida DPF, Gião MS, Pintado M, Gomes MH. Bioactive phytochemicals in apple cultivars from the Portuguese protected geographical indication “Maçã de Alcobaça:” Basis for market segmentation. Int J Food Prop. 2017;20(10):2206–14.

Pirlak L, Ünüvar G, Ersoy N. Determination of antioxidant activities of some apple cultivars. Hortic Sci. 2017;44(3):120–5.

Arda O, Göksügür N, Tüzün Y. Basic histological structure and functions of facial skin. Clin Dermatol. 2014;32(1):3–13.

Wolff K, Johnson RA. Fitzpatrick’s Color Atlas and Synopsis of Clinical Dermatology. New York: McGraw-Hill Companies, Inc; 2018. 1–2000 p.

Chu T, Santos L, McElwee K. Biology of the hair follicle and mechanisms of nonscarring and scarring alopecia. Semin Cutan Med Surg. 2015;34(2):50–6.

Erdoğan B. Anatomy and Physiology of Hair. In: Hair and Scalp Disorders. New York: InTech Open; 2016.

Bouhanna P, Bouhanna E. The Alopecias: Diagnosis and Treatments. First ed. New York: CRC Press; 2015. 23–64 p.

American Academy of Dermatology. Hair loss | American Academy of Dermatology [Internet]. 2019 [diakses tanggal 30-Sep-2019]. Tersedia di:

Kovacevic M, Goren A, Shapiro J, Sinclair R, Lonky NM, Situm M, et al. Prevalence of hair shedding among women. Dermatol Ther. 2016/10/06. 2017 Jan;30(1):e12415.

British Association of Dermatologists. Male Pattern Hair Loss (Androgenetic Alopecia). 2016;(258474):1–4.

Fabbrocini G, Cantelli M, Masarà A, Annunziata MC, Marasca C, Cacciapuoti S. Female pattern hair loss: A clinical, pathophysiologic, and therapeutic review. Int J Women’s Dermatology. 2018;4(4):203–11.

Phillips T, Slomiany W, Allison R. Hair Loss: Common Causes and Treatment. Am Fam Physician. 2017;96(6):371–8.

Prok L, Torres-Zegarra C, William HJ, Levin M, Deterding R, Abzug M. Current Diagnosis & Treatment: Pediatrics. 24th ed. New York: McGraw-Hill Education; 2018.

Papadakis M, McPhee S, Bernstein J. Alopecia. In: Quick Medical Diagnosis & Treatment 2019. New York: McGraw-Hill Education; 2019.

Hosking AM, Juhasz M, Atanaskova Mesinkovska N. Complementary and Alternative Treatments for Alopecia: A Comprehensive Review. Ski Appendage Disord. 2019;5(2):72–89.

Wei G, Martirosyan D. Hair loss: A review of the role of food bioactive compounds. Bioact Compd Heal Dis. 2019;2(5):94–125.

Tenore GC, Caruso D, Buonomo G, D’Urso E, D’Avino M, Campiglia P, et al. Annurca (Malus pumila Miller cv. Annurca) apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels: results of a randomized clinical trial. J Sci Food Agric. 2017 May;97(7):2107–15.

D’Angelo S, Martino E, Ilisso CP, Bagarolo ML, Porcelli M, Cacciapuoti G. Pro-oxidant and pro-apoptotic activity of polyphenol extract from Annurca apple and its underlying mechanisms in human breast cancer cells. Int J Oncol. 2017 Sep;51(3):939–48.

Riccio G, Sommella E, Badolati N, Salviati E, Bottone S, Campiglia P, et al. Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward beta-Oxidation. Nutrients. 2018 Nov;10(11):1–7.

Tenore GC, Caruso D, Buonomo G, D’Avino M, Santamaria R, Irace C, et al. Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth and Tropism in a Randomized Clinical Trial. J Med Food. 2018 Jan;21(1):90–103.

Stirpe M, Palermo V, Bianchi MM, Silvestri R, Falcone C, Tenore G, et al. Annurca apple (M. pumila Miller cv Annurca) extracts act against stress and ageing in S. cerevisiae yeast cells. BMC Complement Altern Med. 2017 Apr;17(1):200.

Ornelas J, Sivamani RK. The Role of Botanical Products in the Treatment of Alopecia. Hair Ther Transplant. 2014;5(2):2–7.




How to Cite

Chintya Redina Habsari, Merry Indah Sari, & Yulisna. (2019). The Effect of Apple (Malus sylvestris mill) as a Natural Ingredient to Prevent Hair Loss. Medical Profession Journal of Lampung, 9(2), 205-211.




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