Osteoporosis: Etiology And Management
DOI:
https://doi.org/10.53089/medula.v13i5.781Keywords:
bone density, osteoporosis, fractureAbstract
One of the main public health problems for the elderly, both men and women, is osteoporosis. Many factors accompany problems in the elderly such as aging, menopause, endocrine disorders, weakening of physical activity, as well as side effects of certain drugs, which contribute to complaints of osteoporosis. The presence of osteoporosis results in increased bone fragility while almost all bones are susceptible to fracture. The incidence of fracture events is closely related to the increase in osteoporosis which is indicated by increasing age. Measures to diagnose and prevent osteoporosis and its complications are a major issue and concern at this time as an effort in public health because the increased incidence of fractures is also associated with increasing health care costs and accompanied by physical disability and impaired quality of life, even the effect has an impact on increasing mortality rate. Currently, BMD (bone mass density) measurement is a key factor in identifying patients at risk of fracture. The measurement results of BMD are used as a reference for making treatment therapy decisions, as well as for monitoring the progress of the therapy being undertaken. Several risk factors for osteoporosis have also been identified for their treatment potential, which can be modified and cannot be modified. Treatment of potentially modifiable risk factors along with sports activities accompanied by calcium (Ca) and vitamin D supplements is important information for the management or pharmacological management of osteoporosis.
References
NIH NI of H. National Institutes of Health (NIH) Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy. JAMA. 2001;285(6).
Sozen T, Ozisik L, Calik Basaran N. An overview and management of osteoporosis. Eur J Rheumatol. 2017;4(1).
Mirza F, Canalis E. Secondary osteoporosis: Pathophysiology and management. Vol. 173, European Journal of Endocrinology. 2015.
Drake MT, Clarke BL, Lewiecki EM. The Pathophysiology and Treatment of Osteoporosis. Vol. 37, Clinical Therapeutics. 2015.
Åkesson K, Marsh D, Mitchell PJ, McLellan AR, Stenmark J, Pierroz DD, et al. Capture the Fracture: A Best Practice Framework and global campaign to break the fragility fracture cycle. Osteoporosis International. 2013;24(8).
Tu KN, Lie JD, Wan CKV, Cameron M, Austel AG, Nguyen JK, et al. Osteoporosis: A review of treatment options. Vol. 43, P and T. 2018.
Buckley L, Guyatt G, Fink HA, Cannon M, Grossman J, Hansen KE, et al. 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. Arthritis and Rheumatology. 2017;69(8).
Shahinian VB, Kuo YF, Freeman JL, Goodwin JS. Risk of Fracture after Androgen Deprivation for Prostate Cancer. New England Journal of Medicine. 2005;352(2).
Tannenbaum C, Clark J, Schwartzman K, Wallenstein S, Lapinski R, Meier D, et al. Yield of laboratory testing to identify secondary contributors to osteoporosis in otherwise healthy women. Journal of Clinical Endocrinology and Metabolism. 2002;87(10).
Raisz LG. Pathogenesis of osteoporosis: Concepts, conflicts, and prospects. Vol. 115, Journal of Clinical Investigation. 2005.
Gourlay ML, Fine JP, Preisser JS, May RC, Li C, Lui LY, et al. Bone-Density Testing Interval and Transition to Osteoporosis in Older Women. New England Journal of Medicine. 2012;366(3).
Berry SD, Samelson EJ, Pencina MJ, McLean RR, Cupples LA, Broe KE, et al. Repeat bone mineral density screening and prediction of hip and major osteoporotic fracture. JAMA. 2013;310(12).
Ross AC, Taylor CL, Yatkine AL DVH. Institute of Medicine Committee to Review Dietary Reference Intakes for Vitamin D and Calcium. Dietary. Dietary Reference Intakes for Calcium and Vitamin D. 2011;Washington(National Academies Press).
Kopecky SL, Bauer DC, Gulati M, Nieves JW, Singer AJ, Toth PP, et al. Lack of evidence linking calcium with or without Vitamin D supplementation to cardiovascular disease in generally healthy adults: A clinical guideline from the national osteoporosis foundation and the American society for preventive cardiology. Vol. 165, Annals of Internal Medicine. 2016.
Chung M, Tang AM, Fu Z, Wang DD, Newberry SJ. Calcium intake and cardiovascular disease risk: An updated systematic review and meta-analysis. Vol. 165, Annals of Internal Medicine. 2016.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Medical Profession Journal of Lampung
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.