Therapeutic Management of Acute Kidney Injury (AKI)

Authors

  • Auriva Renasha Suherman Medical Faculty, Lampung University
  • Intanri Kurniati Universitas Lampung
  • Exsa Hadibrata Universitas Lampung

DOI:

https://doi.org/10.53089/medula.v14i2.983

Keywords:

Acute Kidney Injury, Kidney Disease, Therapeutic Management

Abstract

Acute Kidney Injury (AKI) is a syndrome characterized by decreased urine production and increased serum creatinine. AKI is a complication in 10 to 15% of patients in hospital and the incidence of AKI in the Intensive Care Unit (ICU) is 20 to 50%. AKI has 3 stages and based on etiology it is divided into 3, namely pre-renal, renal, and post-renal. AKI can be a complication of disease and can cause complications up to end-stage kidney disease. Biomarkers of AKI are not only a guide in diagnosis, but also a guide in the management of AKI. Prevention and management of AKI needs to be carried out in patients. Several AKI treatments that can be carried out include the administration of isotonic crystalloid, Hydroxerthylstarch, vasopressors, diuretics, vasodilators, GF intervention, glycemic control, and nutritional support.

References

Ricci Z, Cruz D, Ronco C. The RIFFLE criteria and mortality in acute kidney injury: A systematic review. Kidney Int. 2008;73(5):538-546.

Hidayat, Kestriani N, Pradian E. Angka Kejadian, Lama Rawat, dan Mortalitas Pasien Acute Kidney Injury di ARTIKEL PENELITIAN ICU RSUP Dr. Hasan Sadikin Bandung. Jurnal Anestesi Perioperatif. 2020;8(2), 108–118.

Al-Jaghbeer M, Dealmeida D, Bilderback A, Ambrosino R, Kellum J. Clinical Decision Support for In-Hospital AKI. Journal of the American Society of Nephrology. 2018;29(2):654–660.

Kellum JA, Lameire N, Aspelin P, Barsoum RS, Burdmann EA, Goldstein SL, dkk. Kidney disease: Improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury. Kidney International Supplements. 2016;2(1):1-138.

Ronco C, Bellomo R, Kellum JA. Acute kidney injury. The Lancet. 2019;394(10212): 1949–1964.

Peres LAB, Wandeur V, Matsuo T. Predictors of acute kidney injury and mortality in an Intensive Care Unit. Jornal Brasileiro de Nefrologia. 2015: 37(1):38-46.

Triastuti I, Sujana I. Acute Kidney Injury (AKI). Denpasar: Universitas Udayana; 2017.

Meola M, Samoni S, Petrucci I, Ronco C. Clinical Scenarios in Acute Kidney Injury: Post-Renal Acute Kidney Injury. Contributions to Nephrology. 2016;188:64-68.

Xu K, Rosenstiel P, Paragas N, Hinze C, Gao X, Shen TH, dkk. Unique Transcriptional Programs Identify Subtypes of AKI. Journal of the American Society of Nephrology. 2017; 28(6):1729–1740.

Vandenberghe W, Gevaert S, Kellum JA, Bagshaw SM, Peperstraete H, Herck I, dkk. Acute Kidney Injury in Cardiorenal Syndrome Type 1 Patients: A Systematic Review and Meta-Analysis. Cardiorenal Medicine. 2016;6(2):116–128.

Virzì GM, Breglia A, Castellani C, Ankawi G, Bolin C, de Cal M, dkk. Lipopolysaccharide in systemic circulation induces activation of inflammatory response and oxidative stress in cardiorenal syndrome type 1. Journal of Nephrology. 2019;32(5): 803–810.

Zheng L, Gao W, Hu C, Yang C, Rong R. Immune Cells in Ischemic Acute Kidney Injury. Current Protein & Peptide Science. 2019;20(8):770–776.

Virzì GM, Breglia A, Brocca A, de Cal M, Bolin C, Vescovo G, dkk. Levels of Proinflammatory Cytokines, Oxidative Stress, and Tissue Damage Markers in Patients with Acute Heart Failure with and without Cardiorenal Syndrome Type 1. Cardiorenal Medicine. 2018;8(4):321– 331.

Praga M, González E. Acute interstitial nephritis. Kidney International. 2010;77(11):956–961.

Landoni G, Biondi-Zoccai G, Marino G, Bove T, Fochi O, Maj G, dkk. Fenoldopam Reduces the Need for Renal Replacement Therapy and In-Hospital Death in Cardiovascular Surgery: A Meta-Analysis. Journal of Cardiothoracic and Vascular Anesthesia. 2008;22(1):27– 33.

McClave SA, Taylor BE, Martindale RG, Warren M, Johnson D, Braunschweig C, dkk. Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient. Journal of Parenteral and Enteral Nutrition. 2016; 40(2):159–211.

Published

2024-02-07

How to Cite

Suherman, A. R., Kurniati, I. ., & Hadibrata , E. . (2024). Therapeutic Management of Acute Kidney Injury (AKI) . Medical Profession Journal of Lampung, 14(2), 400-404. https://doi.org/10.53089/medula.v14i2.983

Issue

Section

Artikel

Most read articles by the same author(s)

1 2 3 > >>